Do you have COVID-19? With a little training, your dog might be more effective at figuring that out than even at-home antigen or sophisticated hospital tests.
In 1996, of the 72 students who had sat the final BDS examination, 29 (40%) attended the meeting and answered the questionnaire. Similarly in 1997, of the 75 who sat the final exam, 23 (31%) attended the meeting and answered the questionnaire. In 2000 all 80 (100%) students who sat the final exam answered the questionnaire in the dental school. In 2001, of the 78 who sat the final exam, 25 (32%) attended the meeting and answered the questionnaire. In 2002 of the 62 who sat the final exam 55 (89%) answered the questionnaire in the dental school. The meetings, at which the questionnaire was given, were all held outside the dental school. In the five classes all the questionnaires that were given out were returned fully completed. There was no non-response bias in any of the classes.
Because the scores for the skills were in ordinal scales and since the samples from 3 of the 5 classes were relatively small, non parametric statistics was used to test the consistency in the pattern of responses among the five classes. Non-parametric statistics are applicable in situations where trial sizes are small and where no assumptions are made as to the distribution of the data8.
Table 1 gives the rank orders (1 to 46) of the skills for each of the five classes; rank order 1 being least confident and 46 most confident. The statistical correlation of the ranking of the 46 skills among the five different classes was tested using the non-parametric Kendall's 'tau' rank order correlation test9. The results are given in Table 2. It shows a very high degree of correlation (p<.0001) between the rank orders of the skills in the five different classes. This suggests a high degree of consistency in the self- ratings of confidence in the different skills amongst the five different classes.
Table 1 also reveals that all five classes ranked the skills of doing an external cardiac massage; maintaining a clear airway and ventilating a patient; treating common systemic diseases as the three least confident skills. The skills that were ranked among the three most confident skills by the five classes were extracting fully erupted teeth using forceps & elevator; restoring teeth using tooth coloured restorative materials; restoring teeth using amalgam; educating patients on oral diseases and their prevention; carrying out a thorough examination of the mouth; performing scaling and root planning of teeth; diagnosing Caries; carrying out pulp therapy in primary dentition and removing broken teeth.
The 46 skills were grouped into 12 categories (see Table 1). The three categories in which they were least confident were cardiac arrest; oral manifestations of systemic disease and medical emergencies. The three categories in which they were most confident were caries; periodontal disease and paedodontics.
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A University of Queensland study has found a student-led dental clinic in rural Queensland improved the oral health of Aboriginal and Torres Strait Islander peoples by providing access to culturally appropriate and timely care.
The clinic at Dalby in south-west Queensland, opened in 2013 as a partnership between UQ's School of Dentistry and Aboriginal community-controlled health service, Goondir Health Services.
Dr Sandra March from UQ's School of Dentistry said each year the clinic treated approximately 800 Indigenous patients from Dalby and the Greater Western Downs region.
Oral health care is provided free of charge by fifth-year students from UQ's Bachelor of Dental Science (Honours) program under the supervision of registered, experienced dental practitioners.
This model offers benefits for both the students and the surrounding communities.
By the end of 2023, more than 180 students will have completed a rural Indigenous clinical outplacement at the Dalby clinic.
We found this powerful learning environment developed students' skills and knowledge in culturally appropriate dental care."
Dr Sandra March from UQ's School of Dentistry
Associate Professor Ratilal Lalloo from UQ's School of Dentistry said culturally appropriate and timely dental care is often not available to Indigenous people, especially in rural and remote areas.
"Indigenous people suffer from more caries, periodontal disease and tooth loss than non-Indigenous people," Dr Lalloo said.
"We worked with Indigenous people from Goondir Health Services and local community groups to understand the barriers to oral health care."
The student dental clinic was embedded within the Goondir Health Services premises in Dalby.
"Referrals for dental care are integral to Goondir's holistic healthcare model," Dr Lalloo said.
"The community reported increased knowledge of oral health, improved general health outcomes and better access to a culturally safe and appropriate model of care.
"We also found waiting times for the government-funded dental clinic were shorter, indicating our student clinic eased the burden on the public system."
Goondir Health Services CEO Floyd Leedie said the unique partnership could be replicated across a range of allied health fields in regional and rural Australia.
"The two-way relationship between general and oral health and accessibility to both primary health care services and oral health services in one location reduces the chance of negative impacts to our clients' overall health," Mr Leedie said.
The team has published studies in Australian Dental Journal and The Australian Journal of Rural Health.
The two main products used for teeth whitening are hydrogen peroxide and carbamide peroxide. Unlike a whitening toothpaste that uses an abrasive ingredient to mechanically remove surface-level stains, the oxygen molecules within these whitening agents weaken your tooth stains on a molecular level.
Many over-the-counter (OTC) whitening strips, kits and pens also use a form of peroxide. The difference between these and professional teeth whitening is the chemical concentration.
“In the office, we use a very high percentage of hydrogen peroxide because we have the capability to isolate the teeth,” says Joseph Michael Brofsky, head of pediatric dentistry at Cohen Children’s Medical Center of New York. “We use a special rubber dam to protect the patient’s gums because if peroxide gets onto the gums, it would burn them.”
Like at-home whitening products, there are a variety of professional teeth whitening methods. In-office professional whitening is a quicker, albeit more costly way to lighten up your pearly whites. Meanwhile, custom take-home trays fall somewhere between in-office professional whitening and an OTC whitener in terms of treatment time and cost.
In-office professional whitening treatments are typically completed in several short appointments but will depend on your unique needs. A whitening agent is left on for 15- to 30-minute increments, and the entire appointment should take no longer than an hour and a half.
There are a few types of in-office whitening treatments:
Halogen light and laser light increased teeth lightness more than hydrogen peroxide alone, according to a 2016 study in the Journal of Conservative Dentistry. After three weeks, study participants in the halogen and laser light groups still had the white teeth color achieved during treatment while the non-light group had “shade rebound” after just two weeks—initially brightened teeth became darker.
However, some studies show no benefit from using a light tool such as a laser or lamp over a whitening gel alone.
Aside from effectiveness, is light exposure safe for your smile? A 2020 study in Materials found that tooth cells recovered well after LED light-accelerated technology, concluding that most side effects are “temporary and transient.”
In-office whitening typically involves several steps:
Even if you stick to your dentist’s recommended regimen of resisting bright foods, coffee and wine, your teeth may appear a bit darker a few days after whitening. But don’t be discouraged. The dehydration caused by teeth-whitening makes them look immediately bright right after your procedure. After a week, if your teeth are not at your preferred shade, speak with your dentist about whether or not there’s potential for them to become lighter with at-home products or more in-office visits.
While in-office whitening is fast, custom take-home trays require some diligence on the part of the patient. They may be your only treatment or a follow-up treatment to in-office whitening if your dentist believes your smile is prone to getting new stains again soon.
With a professional take-home-tray, your dentist will make an impression of your teeth for a custom-fabricated tray. Because this tray will fit perfectly to the shape of your mouth, it will typically deliver you more comprehensive whitening results than OTC trays. Instead of a hydrogen peroxide-based gel, you’ll most likely get a carbamide peroxide-based gel to place in the tray and use at home. Even though it doesn’t whiten as quickly as a hydrogen peroxide-based gel, you’re less likely to experience sensitivity if you accidentally get it on your gums, cheek or tongue.
The concentration of the gel your dentist gives you for your custom-fit trays ranges from 10% to 38% carbamide peroxide, according to the American Dental Association. Your duration of treatment will also vary, from wearing your tray from two to 10 hours a day, and for up to 28 days. Over-the-counter trays come with a similar percentage of carbamide. The difference in quality is in regards to fit. A custom tray will fit directly around your teeth, giving little room for the gel to slip up to your gums or miss whitening hard-to-reach crevices.
Admission to the GEP MBBS (A101) degree programme at the Faculty of Medicine and Dentistry, Queen Mary University of London is highly competitive.
Over 1000 applications for entry in 2023, approximately 12% of applicants were interviewed and of those, 39% were offered a place.
The number of places expected to be available for September 2024 to the four-year GEP MBBS (A101) degree programme is 39.
A range of criteria is used to assess applicants in the first shortlisting:
Applications which do not meet these minimum requirements will be rejected at this point.
A range of criteria is used to assess applicants in the second shortlisting (selection for interview):
Applications which do not fall within the weighted score for interview will be rejected at this point.
A range of criteria is used to assess applicants in the third shortlisting (offers)
Undergraduate Medicine and Dentistry Admissions Policy 2022-23
University Clinical Aptitude Test (UCAT)
The University Clinical Aptitude Test (UCAT) is an admissions test, used by a consortium of UK Universities and non-UK associate member universities to help select applicants for their medical and dental degree programmes.
It is used in collaboration with other admissions processes such as the UCAS application and academic qualifications.
It is also your opportunity to stand out from other applicants and demonstrate your aptitude for a demanding programme of study.
The UCAT is a computer-based test delivered in Pearson VUE test centres throughout the UK and worldwide. More information on the UCAT and how to register can be found here
How we use the UCAT
Applicants will be selected for interview on the basis of a weighted score compared to other applicants who apply in the same year, and may be comprised of UCAT score and/or weighted scoring of degree for graduates. Selection after interview may consider all assessment factors: interview score, situational judgement test, weighted scoring from degree and UCAT score.
UCAT exemptions/waivers are not granted under any circumstances. If you are unable to take the UCAT for any reason, our advice will be to reapply for the following application cycle.
We require applicants to have an understanding of what a career in medicine involves. The interview will explore your understanding of the realities of a career in medicine, it is therefore essential that applicants gain people-focused experience of providing care or service before submitting their application.
It is important to remember that work experience can take many forms. It can be a voluntary opportunity or a paid job. While shadowing a doctor can be useful, we understand that this is not attainable for everyone. Volunteering in a residential care home, or with a local charity, is just as good a source of experience.
The personal statement is not scored as part of the selection process prior, during or after interview. However, it is considered an important part of your UCAS application as agreed by medical schools as the skills and attributes needed for an ideal medical student:
If shortlisted for interview, your interview panel will have access to your UCAS application and may ask you questions from the information you have provided.
Extenuating circumstances for Prospective Applicants
Applicants who have taken or will take an additional year (or more) to complete their qualifications and achieve the minimum academic entry requirements (e.g. A*AA or 2.1) can only be considered if their extenuating circumstances fall within the Equality and Diversity Act 2010. Extenuating circumstances can not be applied for with regards to a UCAT score. Extenuating circumstances that fall within this criteria must be approved by the EC panel prior to making a UCAS application. Further information on the process and deadline to be considered, please refer to Extenuating Circumstances for Prospective Applicants
If shortlisted, you will be asked to attend an online interview. Interviews will take place between January and February.
Interview panels typically consist of two members of senior academic or clinical staff, a medical student and sometimes a lay selector. Interviews are designed to evaluate the following:
There will be three possible outcomes from the interview:
Decisions will be communicated in March when all interviews have been completed.
Candidates who are unsuccessful cannot be reconsidered for entry within the same cycle but may reapply the following year (if they obtain the relevant qualifications at the first attempt) without prejudice to the new application.
Selection to our courses follows the principles of values-based recruitment and the core values of the NHS.
Non-academic Entry Requirements – GEP MBBS (4 years)
Fitness to practise
Training to be a doctor, and practising medicine, requires more than just the acquisition of knowledge and skills. As a medical student, you will have certain responsibilities that differ from those of other students. Consequently, we expect high standards of professional behaviour from you.
Graduates are entitled to provisional registration with the General Medical Council (GMC) with a licence to practise, subject to demonstrating to the GMC that their fitness to practise is not impaired.
The Faculty for Medicine and Dentistry is responsible for ensuring that students who graduate are fit to practise, according to principles laid down by the GMC. If the conduct of a medical student calls into question their fitness to practise, they may be required to appear before the Fitness to Practise Committee and could be removed from the course.
Disclosure and Barring Service - DBS
All offers of a place on the medical course are subject to a satisfactory Enhanced DBS certificate. The Faculty of Medicine and Dentistry implements strict deadlines for submission of this information. These deadlines are conditions of the offers we make, and students who fail to meet them will be rejected, even if they have fulfilled the academic conditions of their offer.
The cost of the Enhanced DBS check and registration process must be paid for by you. Once you have been offered a place, you will be sent further information on how to obtain an Enhanced DBS certificate.
DBS update service
As a medical student, it is extremely important to use the DBS update service to keep your DBS certificate up to date and to save you time and money of having to go through the process again during your studies. Once you have received your Enhanced DBS, you must register for the update service within 30 days of your certificate being issued. The cost for the DBS update service is £13 per year, payable by you.
Further details are available on the DBS website
UCAS application and criminal convictions
On your UCAS application, you will be asked to declare spent and unspent convictions that would appear on an enhanced DBS certificate.
Occupational Health Checks
The Faculty of Medicine and Dentistry welcomes and accommodates people with health conditions and disabilities. However, medical students must be fit to practise and the safety of patients will always be the primary consideration. We have a strong system of student support and anyone with a health condition or disability will be offered the appropriate adjustments and support to help them succeed. However, in some cases, an impairment or health condition may make it impossible for a student to meet the outcomes required by the GMC at the point of graduation. Where all possible options to help the student have been explored and are still unsuccessful, the student may have to leave the course or be reviewed by the Professional Capability Committee.
If you are offered a place on the course, we will send information regarding the requirement for prior assessment. This will be in the form of a confidential health questionnaire which follows the HEOPS guidance, but also we will ask you to make contact with our Disability and Dyslexia Service. This is so that a discussion of reasonable adjustment or discussion of your assessment of needs report can be made prior to you starting the degree programme. We also have to be assured that we can help you practise safely in training and employment. The Faculty of Medicine and Dentistry has implemented the guidance from the Department of Health on health clearance for new healthcare workers.
Hepatitis B status and vaccination
Immunising medical students against hepatitis B and testing their response protects both them and their patients against the risk of contracting hepatitis B in the healthcare setting. We strongly recommend that all medical students are vaccinated against hepatitis B before entry.
Carriers of blood-borne virus
If you are a known carrier of a blood-borne virus (BBV), you should contact the Occupational Health Service (OHS) for further advice. All medical students are offered BBV testing, and, if appropriate, hepatitis B vaccination, on entry to medical school. Students declining testing or found to test positive for a BBV are not cleared to undertake Exposure-Prone Procedures (EPPs) and will be required to follow an EPP-free curriculum. There may be additional requirements relating to other blood-borne viruses as advice is continuously updated and published by advisory bodies.
Should you have any queries about the health requirements for either the medical or dental programmes, please contact the university Occupational Health Service for advice.
Students with disabilities and health problems
You should read the following paragraphs carefully with regard to personal circumstances that might make it difficult or impossible for you to practise.
Students with disabilities
The Faculty of Medicine and Dentistry welcomes applications from disabled students. We do, however, have a duty to ensure that candidates admitted to our programmes will be eligible for registration by the GMC on graduation. For this reason, students with disabilities should seek advice from the Student Recruitment and Admissions Office before the deadline for UCAS applications so that each case can be given individual attention and consideration.
Advice should be sought well in advance of the UCAS deadline and no less than four weeks before the deadline to ensure time for a response.
Disability and Dyslexia Service
The Disability and Dyslexia Service can offer advice, guidance and practical support to students with specific learning difficulties, such as dyslexia. This support may include screening students for dyslexia and organising formal educational psychologists’ assessments, arranging individual tutorials from specialist dyslexia tutors, additional time in exams and assisting disabled and dyslexic students to apply for the Disabled Students’ Allowance. More details are available from the Disability and Dyslexia Service. Students are encouraged to contact the Service before starting their programme to discuss any specific needs.
The school of Medicine and Dentistry firmly and actively supports an equal opportunities policy. In the case of a specific learning disorder or disability, we would assess any student meeting the required academic standard in accordance with the prescribed professional standards and the Equality Act (2010).
Information from our most accurate admissions cycle can be found here.
SINGAPORE - Starting from August 2023, freshmen joining the National University of Singapore (NUS) to study dentistry, medicine, nursing and pharmacy will take a common set of modules in their first two years, alongside their current individual programmes.
NUS on Tuesday announced that about 870 first-year students across the four healthcare disciplines will take five courses together, as part of a new common curriculum for healthcare professional education that has been designed with Singapore’s preventive care strategy Healthier SG in mind.
The aim is to imbue in students a greater awareness of social issues and their impact on health, as well as cultivate teamwork, communication skills and digital literacy.
The five courses – each of which will be completed within 13 weeks – will cover subjects such as how social and environmental factors influence health outcomes, and data literacy for healthcare.
Students will also learn about working and communicating in multidisciplinary teams, as well as the legal and ethical principles underpinning the practice and delivery of health services.
They will also explore aspects such as computational thinking, data science, artificial intelligence and machine learning in the healthcare context.
Lessons will be conducted through a mix of online and in-person classes.
Students from the four healthcare disciplines will also form mixed teams to visit patients in their homes regularly over a year so that they can apply concepts they learn in class about providing holistic patient care as well as fostering empathy.
Professor Aaron Thean, NUS deputy president for academic affairs and provost, said the changes are a big step in reforming healthcare education to make it more relevant for Singapore’s needs. This is the first time that all four healthcare disciplines are working together, he said.
Professor Chong Yap Seng, dean of the NUS Yong Loo Lin School of Medicine, said: “Health and well-being are more than just caring for the sick. To help people stay healthy as long as they live, and better care for them when they are ill, we need to look beyond the traditional confines of medicine and science, and draw upon other disciplines.”
“Health sciences education should prepare tomorrow’s doctors, nurses, dentists and pharmacists to harness the power of artificial intelligence, computing, business analytics, even music and the arts, in the provision of holistic, patient-centric healthcare,” he added.
Adjunct Professor Lau Tang Ching, vice-dean for education at NUS Medicine, said: “This is something that we have dreamed of since about 10 or 15 years ago – the different schools and faculty have actually always wanted our different professional student groups to come together to learn together.
“But it was very difficult to organise common time for them.”
To free up space for a common curriculum, which makes up 10 per cent to 12 per cent of the overall course load for students, the schools cut back on repetitive content after a review. Courses with similar content across the four disciplines were consolidated.
All first-year medical students in the current academic year 2023/2024 will also need to complete a Minor in Biomedical Informatics during their undergraduate years.
The curriculum combines healthcare, data science, artificial intelligence and information technology to equip students in using data effectively to Improve patient outcomes and information flow across healthcare IT systems.
Prof Chong said this minor was made compulsory to underscore the importance of medical students being equipped with digital skills.
“We don’t want to wait for our doctors to become outdated… by 2027, I’m pretty sure everything is going to be digitalised and AI will be commonplace. So a lot of the tasks that normal house officers do will be completely enhanced by AI, like writing up medical reports,” he said.
From the current academic year, undergraduates from other NUS faculties, schools and colleges can also take up a new Minor in Integrative Health offered by NUS Medicine to learn more about modern healthcare systems.
Students taking this programme, which aims to develop an interdisciplinary mindset in solving complex health issues, will complete five courses over two years or more.
It will start with 50 students, with the intake possibly growing over the next three years.
Professor Bernard Tan, senior vice-provost for undergraduate education, at NUS, said: “Some people will say that in the past, our health sciences curriculum move very slowly. Now that we have done this very major revision, it is also the intention of the university to signal to the rest of the community… that we are prepared to move forward as fast as is needed, in tandem with the developments in the healthcare scenario in Singapore.
“To facilitate this move towards preventive health care and ageing in place, we cannot be training our health sciences professionals like what we did in the past – wait for people to fall sick, and then we fix them.”
Second-year dentistry student Hilary Moh, 21, who took one of the common curriculum courses – social and behavioural determinants on health – as part of a pilot in 2022, said she is better able to see how her field fits into the bigger picture of healthcare, instead of focusing solely on oral care.
Ms Yunn Honey Aye Kyaw, 19, who is in her second year of NUS Medicine and also took the course, said: “I initially went into medicine thinking only about the physical aspects of health, so it is eye-opening to see the non-medical factors that affect patients’ health.”
Covers medically-required services, such as visits to doctors, hospital stays and diagnostic medical testing.
International exchange or study abroad students: you will be automatically enrolled in a mandatory 4 month primary medical insurance plan through guard.me@SFU. Depending on how long you are studying at SFU, you may be applying for the BC Medical Services Plan (MSP) as well.
Domestic (inter-provincial) exchange students: within Canada (including students who are international students at their home institutions), you are expected to maintain primary medical insurance in your home province.
Generally covers services such as vision care, prescription drugs, dental care, and more.
Exchange students (paying tuition to home institution): you will not receive a secondary medical insurance plan through SFU. You may wish to purchase coverage through a private insurance agent. The guard.me@SFU plan includes some limited secondary benefits.
Study Abroad students (paying tuition to SFU): you will receive secondary medical insurance through the SFSS/GSS Extended Health and Dental Plan.
Do you have COVID-19? With a little training, your dog might be more effective at figuring that out than even at-home antigen or sophisticated hospital tests.
Dogs are so good at it, according to a new research review, that they may be ready for mainstream medical use if people didn’t consider this a curiosity rather than a real possibility.
Man’s best friend can be faster, more precise and less expensive at detecting COVID than standard tests, according to the review of a growing number of studies.
Over the past couple of years, “it went from four papers to 29 peer-reviewed studies -- that includes more than 400 scientists from over 30 countries and 31,000 samples,” said co-author Tommy Dickey, an emeritus professor of geography at the University of California, Santa Barbara.
While vast quantities of peels from the aloe vera plant are thrown out every year as agricultural waste, this natural ingredient has potential to be a powerful insecticide, new research suggests.
“It’s likely that millions of tons of aloe peels are disposed of globally every year,” said principal investigator Debasish Bandyopadhyay, from the University of Texas Rio Grande Valley. “We wanted to find a way to add value and make them useful.”
The plant’s rinds can naturally ward off bugs because of several bioactive compounds found in extracts from the peels.
The researchers will present their results this week at the fall meeting of the American Chemical Society, held online and in San Francisco.
Damaged teeth could one day be repaired with “living fillings” created from stem cells, a new study reports.
In the lab, researchers induced stem cells to form small, multicellular mini-organs that secrete the proteins that form tooth enamel, according to a report published Aug. 14 in the journal Developmental Cell.
“This is a critical first step to our long-term goal to develop stem cell-based treatments to repair damaged teeth and regenerate those that are lost,” co-author Dr. Hai Zhang, a professor of restorative dentistry at the University of Washington School of Dentistry, said in a school news release.
Tooth enamel is the hardest tissue in the human body. It protects teeth from the mechanical stresses of chewing and helps them resist decay, researchers said in background notes.
Teens’ desire to start smoking, and later to keep smoking, may be linked to differences in gray matter in their brains, a new study reveals.
Researchers found that reduced gray matter in the left frontal lobe was found in kids who started smoking by age 14. This area is involved in decision-making and rule-breaking.
Once they started smoking, they also had reduced gray matter in the right frontal lobe, a region associated with seeking pleasure.
“Smoking is perhaps the most common addictive behavior in the world, and a leading cause of adult mortality,” said co-senior author Trevor Robbins, a professor in the Department of Psychology at the U.K.'s Cambridge University. “The initiation of a smoking habit is most likely to occur during adolescence. Any way of detecting an increased chance of this, so we can target interventions, could help save millions of lives.”
It’s fun to playfully toss a toddler into the air, or tote a kid piggyback-style on your shoulders.
But those delightful giggles may come with a risk of head injury from a typically overlooked hazard -- the room’s ceiling fan.
Each year U.S. emergency rooms treat about 2,300 children for head injuries caused by ceiling fans, according to Consumer Product Safety Commission data collected between 2013 through 2021.
These ER-treated injuries totaled more than 20,500 over the period, a new study in Pediatrics reports.
And there are probably a lot more that go uncounted, said lead researcher Dr. Holly Hughes Garza, an epidemiologist at Dell Children’s Trauma and Injury Research Center in Austin, Texas.
Women who have larger breasts tend to exercise less or less intensely, according to a new study that suggests having breast reduction surgery could be a game changer.
Australian researchers looking at exercise participation for women in this category called for more accessible, publicly funded breast reduction and other interventions.
The study used survey results from nearly 2,000 women who were in the involved in the Parkrun program, which promotes 5K running and walking events. Participants were in Australia, England and South Africa.
Women with bigger breasts reported that reducing their breast size would Improve their exercise performance and frequency. And among the survey participants, the 56 women who had already undergone breast reduction surgery said they lead healthier and more active lifestyles.
Muscle cramps can be sudden and excruciating. What causes them and what will make them go away — fast?
An emergency room doctor offered tips on treating, preventing and stopping these painful episodes in their tracks.
“Muscle cramps or excessive nerve stimulations in the muscles … are caused by stress to … the nerves within our muscles,” said Dr. Patrick McHugh, a specialist in emergency medicine at the Cleveland Clinic. “Causes include conditions such as low magnesium, low calcium, low thyroid [activity] or the kidneys or the liver being affected by dehydration and electrolyte imbalances.”
But that's not all, he added.
Magenta Medical announced today that it completed enrollment for the early feasibility study of its Elevate heart pump device.
The FDA-approved study evaluates the percutaneous left ventricular assist device (pLVAD) for high-risk percutaneous coronary intervention (HR-PCI). Investigators enrolled and successfully treated 15 study patients. Treatments took place at Mount Sinai Hospital, St. Francis Hospital and Heart Center and North Shore University Hospital.
Magenta won FDA approval to evaluate the safety and feasibility of Elevate in providing temporary mechanical support in HR-PCI procedures. It constitutes the first step in a clinical program aimed at securing approval for Elevate — the world’s smallest heart pump — in the U.S.
Dr. Samin Sharma, director of interventional cardiology at Mount Sinai, performed the first U.S. procedure. Sharma cited “three cardinal features” of Elevate — small insertion profile, ease of use and high pump flow. He said these enable surgeons to benefit many more appropriate selected complex PCI patients.
Sharma also noted the ability to navigate the device smoothly, despite hostile vascular environments.
Magenta’s high-flow, low-profile device holds a duo of FDA breakthrough device designations. The agency deemed it a breakthrough option for high-risk percutaneous coronary intervention and cardiogenic shock. Magenta completed a first-in-human study in Tbilisi, Georgia, and presented results last year.
The company now plans to launch clinical programs in the U.S., beginning with this early feasibility study. Earlier this year, Magenta raised $55 million in a financing round geared toward advancing these programs toward FDA approval.
The proprietary technology miniaturizes the powerful, percutaneous LVAD to fit an 8 Fr delivery system. Magenta says this marks the smallest crimping profile of any such device.
Inserted over a guidewire, through the aorta and across the aortic valve using 10 Fr introducer sheaths, the system offers ease of use, safety, physician access and vascular access closure. Once deployed, the speed of the pump can adjust to provide more than 5 L/min of mean blood flow at physiological blood pressures.
Magenta says that represents the full cardiac output of an adult. Its peak flows exceed 7 L/min, making it the most powerful known percutaneous pump.
“Magenta is honored to have partnered with top cardiology centers in the US to further validate its technology and provide cardiologists with a powerful tool to support their high-risk patients during complex procedures,” said Dr. David Israeli, CEO of Magenta Medical. “We are thrilled to have completed enrollment so quickly, which speaks to both the clinical need and the wonderful enthusiasm and support of our clinical partners. The Magenta team is looking forward to offering the advantages of the Elevate System to a wide range of complex cardiac patients in our expanding clinical program towards eventual market approval.”
There are five units of study on the programme, each 20 credits, with the exception of the dissertation, which is 40 credits. The units are:
Introduction to Bioethics: Provides an introduction to the whole field of bioethics, covering key theories and debates, by reference to selected ethical issues in medicine and science, and key skills in researching, and arguing and writing in bioethics. The unit is led by the Centre for Ethics in Medicine and is primarily taught via seminars and assessed via a written essay.
Introduction to Medical Law: Provides a basic grounding in medical law, introducing legal studies and key themes and issues in medical law, as well as exploring the interface of medical law and bioethics. The unit is led by the Centre for Ethics in Medicine and is primarily taught via seminars and assessed via a written essay.
Medicine and Law: Explores the general principles of medical law and allows for a detailed study of specific subjects within the field. The unit is led by the Law School and is primarily taught via lectures and tutorials, and assessed via written assignments.
Ethics: Examines issues in normative ethics, metaethics, practical ethics, and/or the history of ethics. The unit is led by the Department of Philosophy is primarily taught via lectures and tutorials, and assessed via a written examination.
Dissertation: Provides the opportunity to pursue self-selected, independent research work in bioethics. Students also have the opportunity to run a conference, in which guest speakers feature and students’ dissertation subjects can be presented. The unit is led by the Centre for Ethics in Medicine and is primarily taught via seminars and one-to-one supervision, and assessed via a written dissertation.
The programme encourages student-directed study and, in the dissertation, provides the opportunity for students (under supervision) to research subjects and issues of particular interest to them. Examples of past student dissertations include: