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Killexams : CA-Technologies Administrator Free PDF - BingNews https://killexams.com/pass4sure/exam-detail/CAT-040 Search results Killexams : CA-Technologies Administrator Free PDF - BingNews https://killexams.com/pass4sure/exam-detail/CAT-040 https://killexams.com/exam_list/CA-Technologies Killexams : Delivering the next generation of breakthrough genomic medicines

During the pandemic, several of Danaher Corporation’s global science and technology companies pivoted to help scientists and drug developers analyse the SARS-CoV-2 virus and support the generation of new vaccines to combat COVID-19. Achievements include significant contributions to the research and development (R&D) of clinical diagnostics methods and tools for COVID-19, and support for the commercial development of the University of Oxford–AstraZeneca and Moderna vaccines. These accomplishments were founded on early investment and innovation in the genomic medicines space, aimed at providing genomic medicine developers the dedicated tools, services and expertise they need, at every scale and every stage, from the academic bench through to the industrial manufacturing facility and, finally, to the clinic (Fig. 1).

Figure 1. Unlocking the full potential of the genome. Genomic medicines are being developed to treat disease at several organ, tissue and cell targets.

The past five years have witnessed United States Food and Drug Administration approval and commercial launch of 20 drug products in the genomic medicine space, including 6 viral vector gene modified cell therapies for cancer, 2 adeno-associated viral (AAV) vector therapies for rare genetic diseases, 3 small interfering RNA (siRNA) therapies, 4 antisense oligonucleotide (ASO) therapies, 3 adenovirus (Ad) vector-based vaccines, and 2 messenger RNA (mRNA) vaccines for COVID-191. These drug approvals were enabled, in part, by decades of scientific and technological advancements in delivery platforms. These include the refinement of Ad vectors to Excellerate their safety profile, the discovery of new AAV serotypes, the evolution of lipid nanoparticle (LNP) engineering, the discovery of CRISPR–Cas9, and the suite of chemical modifications for oligonucleotides that Excellerate their resistance to nuclease degradation and safety in vivo.

Despite these advancements, the current toolbox of delivery technologies has major limitations. To deliver the next generation of breakthrough genomic medicines, the field will have to double down on cross-disciplinary R&D efforts focused on the development of new delivery technologies, hence this short feature will focus exclusively on delivery.

Lipid nanoparticle delivery: ripe for innovation

All of the approved mRNA vaccines for COVID-19 and one of the siRNA-based therapies use LNPs to deliver their cargo to the cells of interest. The successful mRNA vaccine efforts have spurred a new generation of innovation beyond infectious disease. For example, preliminary results from an ongoing trial have shown that a CRISPR–Cas9-based mRNA drug can be delivered into the body using LNPs to target the liver and reduce expression of the gene that causes transthyretin amyloidosis (ATTR)2.

Despite these successes, LNP-enabled RNA medicine is a field ripe for innovation. For instance, the formulation of RNA payloads into LNPs is critical for efficacy because charged nucleic acids are unlikely to spontaneously cross the lipid bilayer of cell membranes into the cytoplasm where they are biologically active3. Currently, there are multiple methods for assembling LNPs that encapsulate nucleic acids. However, the resulting LNP drug products can vary in potency depending on the method used. And not all of these methods are scalable.

There is substantial opportunity for innovations to bridge the gap between manufacturing large volumes of a vaccine product and the smaller scale multi-product manufacturing better suited for cancer, rare disease and engineered cell therapy applications. With regards to drug targeting, LNP delivery into specific cell and tissue populations remains a challenge. Pre-clinical proof-of-concept studies suggest that there are novel LNP formulations that can go beyond liver and intramuscular applications. Yet, there remains a major need for clinical translation of these novel LNP formulations.

Adeno-associated viral vectors: opportunities and challenges

AAV-based therapies, by contrast, have shown the potential for serotype-dependent tissue specificity. To date, hundreds of AAV serotypes have been isolated from nature or synthetically designed in the lab, each with a unique physical capsid structure and biological attributes. AAV6, for example, is known to target skeletal muscle, AAV8 is a workhorse for liver-based applications, and AAV9 has been shown to cross the blood–brain barrier and enable delivery of a therapeutic payload to the central nervous system (CNS). Coupled with capsid engineering, transgene optimization and synthetic cell-specific promoter designs, AAVs can serve as an effective chassis for enabling the next generation of targeted tissue delivery4.

Unlike LNPs, AAVs have encountered challenges in manufacturing scaleup and analytical characterization limiting their use to rare and orphan genetic diseases. Much of these challenges are a function of the physical complexity of an AAV virion and the cell line-based manufacturing systems. An aspirin molecule is composed of 21 atoms. A standard monoclonal-based biologic medicine is composed of 25,000 atoms. By contrast, a standard AAV drug product is composed of millions of atoms and is a heterogenous mixture of full and empty capsids. For a personalized viral vector gene modified cell therapy, like chimeric antigen receptor (CAR)-T cell therapy, the complexity increases by orders of magnitude. There is a significant need for new drug manufacturing and analytical workflows that enable the scaleup and characterization of AAV and viral vector-based therapies for clinical and commercial applications.

Challenges such as the elimination of host cell proteins and other potential contaminants, including adventitious viruses, from the final drug product can be addressed using both traditional solutions applied in new ways, such as filters upstream in the production process, and novel technological approaches such as microflow liquid chromatography with tandem mass spectrometry (LC-MS/MS). In parallel, there is a need for fully integrated data capture, data mining, and informatics tools that can mine the full complexity of these manufacturing workflows and enable continuous process improvements. This could include the incorporation of in-line analytics based on new methods such as capillary isoelectric focusing (cIEF) for precisely determining the ratio of empty, full and partially filled AAV capsids, to quickly and accurately inform decisions and enable prompt and effective resolution.

Next-generation drug delivery

In the past few months, clinical holds and patient deaths in the AAV viral vector gene therapy space have shown the limitations of the current generation of delivery technologies. On a positive note, recent months have also witnessed significant pre-clinical activity and innovations in delivery approaches. For example, several recent reports have described the development and application of engineered DNA-free virus-like particles (eVLPs) that efficiently package and deliver base editor or Cas9 ribonucleoproteins within the context of in vivo gene editing applications5. Likewise, there have been significant innovations in the development of novel chemical, physical, polymer, peptide, exosome and protein-based delivery modalities6.

The COVID-19 pandemic has highlighted the power of genomic medicine, wherein scientists were able to go from sequencing the genetic code of SARS-CoV-2 to a functional vaccine with over 90% efficacy in less than a year. The rapid pace of development was enabled, in part, by decades of basic and translational research focused on developing and optimizing LNP technologies.To unleash the next generation of breakthrough medicines, we will need to Excellerate upon the current generation of delivery technologies while simultaneously adding new tools to the delivery armamentarium. These types of efforts are going to require focused and dedicated cross-disciplinary initiatives that harness the best of chemistry, engineering, biology, computational informatics, manufacturing, regulatory and drug development expertise.

With a view to supporting these initiatives, we at Danaher and our family of life science companies have expanded our commitment to the genomic medicine space by bringing on board new leaders who share a wealth of expertise and extensive experience in gene therapy, cell therapy and molecular oncology among other disciplines. In parallel, Danaher continues to invest in new innovations and partner with like-minded organizations in academia, government, the non-profit sector and industry to help advance the field. These are just a few of the ways that Danaher is contributing towards supporting the discovery and development of new genomic medicines for the patients who need them. Being part of the genomic medicine community enables us to deliver on our shared purpose of helping realize life’s potential.

Authors

Sadik Kassim1, Chief technology officer (genomic medicines);

James Taylor2, General manager and co-founder;

Vanessa Almendro3, Vice president, science and technology innovation;

Clive Glover4, General manager, gene therapy;

Venkata Indurthi5, Chief scientific officer;

Mark Behlke6, Chief scientific officer.

ADDRESSES

1. DH Life Sciences, LLC, 701 Gateway Blvd, Ste 320, San Francisco, CA 94080, USA.

2. Precision NanoSystems, Inc., #50 655 W Kent Ave N, Vancouver, BC V6P 6T7 Canada.

3. Danaher Corporation, 2200 Pennsylvania Avenue NW, Suite 800W, Washington, DC 20037, USA.

4. Pall Corporation, 20 Walkup Drive, Westborough, Massachusetts 01581, USA.

5. Aldevron, 4055 41st Avenue South, Fargo, North Dakota 58104, USA.

6. Integrated DNA Technologies (IDT), 1710 Commercial Park, Coralville, Iowa 52241, USA.

The following companies are all life sciences companies of Danaher Corporation: DH Life Sciences, LLC, Precision NanoSystems, Inc; Pall Corporation; Aldevron; and Integrated DNA Technologies (IDT).

Sun, 29 May 2022 23:15:00 -0500 en text/html https://www.nature.com/articles/d42473-022-00188-w
Killexams : The Innovation Pyramid

'The Innovation Pyramid clarifies the true meaning of innovation and dispels many popular misconceptions. It is not only a great resource for practitioners trying to innovate but also for executives trying to embed innovation capabilities in their organization.'

Ravi Shanker - Global Business Advisor, The Dow Chemical Company

'Faley provides a definitive process to achieve success, laid out in a manner to ensure such a result.  The examples provided help put a complex process in context.  We can now all be successful innovators guided by his insights.'

Richard Warburg - Partner, New Ventures Funds

'Between 1870 and 1970 America had one of the greatest periods of economic growth in all recorded history.  The reason was the vast number of innovations including electricity, the automobile, telephone, sewer, electric refrigerator, antiseptic surgery, x-rays, antibiotics and running water.  Since then, both economic growth and productivity have been disappointing.  America desperately needs transformative technologies like the 1870-1970 period.  Dr. Tim Faley, one of the world's experts on innovation, tells us how to do it in a book which is a must read for everyone who cares about America's future.'

Kiril Sokolof - Chairman & Founder, 13D Global Strategy & Research

‘Anyone interested in Innovation should read The Innovation Pyramid - not only does Dr. Faley de-mystify innovation and the innovation process, re-framing some of the narrative about innovation along the way, but also describes a methodology and tools by which innovation can be learned and repeated. This book takes a wholistic and insightful look at the raw ingredients needed for creating innovation, and with the author’s gift for making complex courses easily understandable, presents a practical, common-sense framework for describing problems, identifying root-causes, and delivering effective solutions.’

Michael Sharer - Texas A&M University

Sun, 04 Apr 2021 22:37:00 -0500 en text/html https://www.cambridge.org/core/books/innovation-pyramid/64D2D54A7671AE1A4FAEE0085E1D3CA5
Killexams : Corporate Training Market in US to Record a CAGR of 10%, Emergence of Cost Effective E-learning Training Modules to Boost Market Growth - Technavio

NEW YORK, Aug. 8, 2022 /PRNewswire/ -- The "Corporate Training Market in US by Product (Technical courses and Non-technical courses) and End-user (Manufacturing, Healthcare, BFSI, IT, and Others) - Forecast and Analysis 2021-2025" report has been added to Technavio's offering. The potential growth difference for the corporate training market size in the US between 2020 and 2025 is USD 19.51 bn. To get the exact yearly growth variance and the Y-O-Y growth rate, Request a demo Report.

Technavio has announced its latest market research report titled Corporate Training Market in US Growth, Size, Trends, Analysis Report by Type, Application, Region and Segment Forecast 2021-2025

Key Market Dynamics:

  • Market Driver: Emergence of cost-effective e-learning training modules
  • Market Challenge: Growing prominence of MOOCs in corporate learning

Technavio helps businesses be up-to-date with key drivers, trends, and challenges. View our FREE PDF demo Report

Vendor Landscape

The corporate training market in the US is fragmented, with the presence of several international and regional players. Vendors are deploying various organic and inorganic growth strategies to compete in the market. Corporate organizations are collaborating with vendors for the development and implementation of technical and non-technical training through digital tools owing to the rapid shift toward digitalization. Established international vendors that provide corporate training services in the US have a competitive edge in the market owing to their high investment capabilities, brand name, and large scale of operations. However, new entrants have low entry barriers due to relaxed regulations and easy access to distribution channels.

Market Segmentation

By product, the technical training segment will contribute the highest market share growth during the forecast period. Technical courses focus on training employees on knowledge and skills that are essential and relevant to specific industries. These courses largely include training related to plant or facility management, new recruitment fundamentals, product and software feature training, programming language training, sales training, and process safety management, among others. Vendors in the corporate training market in the US offer a range of blended, offline, and online technical courses for a variety of technical requirements. Organizations are increasingly adopting blended learning approaches to train their employees on technical courses. They are encouraging employees to undergo online skill-based training courses and assessments due to constraints related to the shortage of man-hours and the increase in overall training expenses. They also organize instructor-led classroom-based training sessions to clarify doubts and enable interactive real-time discussions related to technical skill sets and product knowledge between instructors and employees. The adoption of video-based, simulation-based, and game-based elements in technical courses improves employee engagement and ensures knowledge retention.

The growth of this segment is expected to remain steady during the forecast period owing to the increasing need for skilling employees. Moreover, government initiatives are expected to fuel the growth of manufacturing jobs, which will increase the need for offering technical training to employees in the manufacturing sector during the forecast period.

Learn about the contribution of each segment summarized in concise infographics and thorough descriptions. View a FREE PDF demo Report

Some Companies Mentioned

  • Adobe Inc.
  • Cisco Systems Inc.
  • City & Guilds Group
  • D2L Corp.
  • Franklin Covey Co.
  • GP Strategies Corp.
  • John Wiley & Sons Inc.
  • NIIT Ltd.
  • Skillsoft Ltd.
  • Wilson Learning Worldwide Inc.

Want your report customized? Speak to an analyst and personalize your report according to your needs.

Related Reports

Corporate Leadership Training Market Growth, Size, Trends, Analysis Report by Type, Application, Region and Segment Forecast 2022-2026

Corporate Training Market in Europe Growth, Size, Trends, Analysis Report by Type, Application, Region and Segment Forecast 2022-2026

Corporate Training Market In US Scope

Report Coverage

Details

Page number

120

Base year

2020

Forecast period

2021-2025

Growth momentum & CAGR

Accelerate at a CAGR of 10%

Market growth 2021-2025

USD 19.51 billion

Market structure

Fragmented

YoY growth (%)

9.31

Regional analysis

US

Performing market contribution

US at 100%

Key consumer countries

US

Competitive landscape

Leading companies, competitive strategies, consumer engagement scope

Companies profiled

Adobe Inc., Cisco Systems Inc., City & Guilds Group, D2L Corp., Franklin Covey Co., GP Strategies Corp., John Wiley & Sons Inc., NIIT Ltd., Skillsoft Ltd., and Wilson Learning Worldwide Inc.

Market Dynamics

Parent market analysis, market growth inducers and obstacles, fast-growing and slow-growing segment analysis, COVID-19 impact and future consumer dynamics, and market condition analysis for the forecast period.

Customization purview

If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized.


Browse Consumer Discretionary Market Research Reports

Key courses Covered:

Executive Summary

Market Landscape

  • Market ecosystem
  • Value chain analysis

Market Sizing

  • Market definition
  • Market segment analysis
  • Market size 2020
  • Market outlook: Forecast for 2020 - 2025

Five Forces Analysis

  • Bargaining power of buyers
  • Bargaining power of suppliers
  • Threat of new entrants
  • Threat of substitutes
  • Threat of rivalry
  • Market condition

Market Segmentation by Product

  • Market segments
  • Comparison by Product
  • Technical courses - Market size and forecast 2020 - 2025
  • Non-technical courses - Market size and forecast 2020 - 2025
  • Market opportunity by Product

Market Segmentation by End-user

  • Market segments
  • Comparison by End-user
  • Manufacturing - Market size and forecast 2020 - 2025
  • Healthcare - Market size and forecast 2020 - 2025
  • BFSI - Market size and forecast 2020 - 2025
  • IT - Market size and forecast 2020 - 2025
  • Others - Market size and forecast 2020 - 2025
  • Market opportunity by End-user

Market Segmentation by Method

  • Market segments
  • Comparison by Method
  • Blended learning - Market size and forecast 2020 - 2025
  • Offline learning - Market size and forecast 2020 - 2025
  • Online learning - Market size and forecast 2020 - 2025
  • Market opportunity by Method

Customer landscape

  • Volume driver - Demand led growth
  • Market challenges
  • Market trends

Vendor Landscape

  • Overview
  • Vendor landscape
  • Landscape disruption

Vendor Analysis

  • Vendors covered
  • Market positioning of vendors
  • Adobe Inc.
  • Cisco Systems Inc.
  • City & Guilds Group
  • D2L Corp.
  • Franklin Covey Co.
  • GP Strategies Corp.
  • John Wiley & Sons Inc.
  • NIIT Ltd.
  • Skillsoft Ltd.
  • Wilson Learning Worldwide Inc.

Appendix

  • Scope of the report
  • Currency conversion rates for US$
  • Research methodology
  • List of abbreviations

About Us

Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provide actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions.

With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

Contact
Technavio Research
Jesse Maida
Media & Marketing Executive
US: +1 844 364 1100
UK: +44 203 893 3200
Email: [email protected]
Website: www.technavio.com/

Technavio (PRNewsfoto/Technavio)

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Mon, 08 Aug 2022 12:43:00 -0500 text/html https://www.tmcnet.com/usubmit/2022/08/08/9651752.htm
Killexams : Expanded Limitations Period and Individual Liability for Employers Facing Labor Commissioner Hearings

Monday, August 8, 2022

An employee in California has two primary options to pursue a claim for the enforcement of minimum wage and overtime pay rights. The employee may seek judicial relief by filing an ordinary civil action. Alternatively, the employee can initiate an administrative action with the Division of Labor Standards Enforcement (DLSE). In Elsie Seviour-Iloff v. LaPaille, the California Court of Appeal set forth multiple important holdings expanding the scope and potential liability available to employees pursuing administrative relief for wage claims with the DLSE.

Background

Bridgeville Properties, Inc. (“BPI”) owned property in Humboldt County, California, which included eight rental units, a post office, and its own water system. During the relevant time period, Cynthia LaPaille served as BPI’s Chief Executive Officer and Chief Financial Officer.

Between 2009 and 2016, Elsie Seviour-Iloff and Laurance Iloff (“plaintiffs”), performed various tasks and odd jobs for BPI in exchange for free rent, but no other compensation. BPI eventually terminated the plaintiffs for suspected misconduct. 

On January 31, 2017, the plaintiffs each filed DLSE form 1, entitled “Initial Report or Claim,” with the Labor Commissioner. The Initial Report or Claim identified the employer, set forth wage information, and identified hours worked. Both plaintiffs alleged being owed $132,880. 

On May 17, 2017, the plaintiffs each executed a form entitled “Complaint,” which set forth the claimed regular and overtime wages contained in the Initial Report or Claim forms, but also included a request for liquidated damages and waiting time penalties. 

The Labor Commissioner concluded the plaintiffs were entitled to recover regular wages, overtime wages, liquidated damages, interest, and waiting time penalties, and that LaPaille was personally liable for those amounts. 

LaPaille and BPI appealed to the Superior Court. Following a five-day trial, the trial court concluded the plaintiffs were entitled to minimum wages and interest, statutory damages for BPI’s failure to provide a wage statement, waiting time penalties, and travel expense reimbursements. But, it declined to award liquidated damages for the minimum wage violations and concluded LaPaille was not personally liable. The plaintiffs then appealed.

The Court of Appeal’s Decision Expands Scope of Relief Available at Labor Commissioner Hearings

The plaintiffs raised several different arguments to the trial court’s judgment that resulted in important rulings for employers from the Court of Appeal.

Statute of Limitations

First, the plaintiffs argued that the trial court erred by calculating the statute of limitations for their unpaid wage claims from the date they filed Complaints, rather than the date they filed their Initial Report or Claim forms, with the Labor Commissioner. The Court of Appeal agreed that the filing of the Initial Report or Claim form initiates the “Berman” hearing procedure, the process by which employees seek administrative relief by filing a wage claim with the Labor Commissioner pursuant to a special statutory scheme set forth in Labor Code §§ 98 – 98.8.

The court explained that, because the plaintiffs used a form provided to them by the DLSE to initiate a wage claim, the Initial Report or Claim contained substantially all the information required to be included based upon the applicable Code of Regulations. In the court’s view, a contrary finding would undermine the accessible and more streamlined nature of the administrative forum for wage disputes.

Individual Liability

The Court of Appeal next examined whether Labor Code § 558.1 granted the trial court discretion to decide whether to impose such individual liability on LaPaille. Labor Code § 558.1 provides: “(a) Any employer or other person acting on behalf of an employer, who violates, or causes to be violated, any provision regulating minimum wages . . . may be held liable as the employer for such violation.” 

Before examining the trial court’s discretion, the Court of Appeal first determined that a private right of action to sue exists under Labor Code § 558.1. Pointing to both the non-exclusive administrative enforcement scheme for wage disputes, as well as the legislative desire to discourage employers from defaulting on wage judgments, the court held that Section 558.1 is not solely limited to enforcement by the Labor Commissioner.

The Court of Appeal then concluded that the statute grants discretion to the party prosecuting the action, not the court, because the prosecuting party may decide not to pursue individual liability if the employee is able to collect on the judgment from the employer. The court held that Section 558.1 does not grant judicial discretion in imposing liability if the individual is, in fact, someone who “violates, or causes to be violated” minimum wage laws.

Good Faith Defense to Liquidated Damages

The Court of Appeal affirmed that the trial court has considerable discretion to determine whether an employer has established the “good faith” defense to liquidated damages.

Labor Code § 1194.2 provides for liquidated damages where an employer has failed to pay the minimum wage. The California Supreme Court has commented that the liquidated damages allowed in Section 1194.2 are in effect a penalty equal and in addition to the amount of unpaid minimum wages. 

As the court noted, Section 1194.2 simply allows a court to exercise discretion in awarding liquidated damages if the employer demonstrates good faith and that the employer had reasonable grounds for believing it was not violating any Labor Code provision.

Under the unique facts in LaPaille, which involved a “barter situation” that the plaintiffs themselves proposed, the Court of Appeal affirmed the trial court’s finding that the employer acted in good faith and did not err in declining to award, in addition to the wages owed plus interest, the additional penalty of liquidated damages.

Calculation of Waiting Time Penalties

As to waiting time penalties owed on unpaid wages, the Court of Appeal held that the trial court failed to include the value of the plaintiffs’ housing when calculating the daily rate of pay. The court ultimately held that the value of the rent should have been incorporated into the calculation of the plaintiffs’ daily wages for purposes of calculating the amount of penalties under Labor Code § 203. 

Conclusion 

The Court of Appeal made important rulings that potentially could impact employers going forward, including as to the scope of relief available to employees pursuing employers and individuals for unpaid wages, in Berman hearings and beyond. Employers should consult their employment counsel to ensure they are complying will applicable Labor Code provisions. 

Copyright © 2022, Sheppard Mullin Richter & Hampton LLP.National Law Review, Volume XII, Number 220

Mon, 08 Aug 2022 10:53:00 -0500 en text/html https://www.natlawreview.com/article/expanded-limitations-period-and-individual-liability-employers-facing-labor
Killexams : A Textbook of Clinical Embryology

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Thu, 01 Apr 2021 19:49:00 -0500 en text/html https://www.cambridge.org/core/books/textbook-of-clinical-embryology/3A2CB1C75CA707B3D1A395D87757EE6D
Killexams : Nestlé reports half-year results for 2022

Nestlé S.A.

[Ad hoc announcement pursuant to Art. 53 LR]

This press release is also available in Français (pdf) and Deutsch (pdf)

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Report published today
2022 Half-Year Report (pdf)

Other language versions available in Publications

.............


Vevey, July 28, 2022

Nestlé reports half-year results for 2022

  • Organic growth reached 8.1%, with real internal growth (RIG) of 1.7% and pricing of 6.5%. Growth was broad-based across most geographies and categories, with increased pricing and resilient RIG.

  • Total reported sales increased by 9.2% to CHF 45.6 billion (6M-2021: CHF 41.8 billion). Net acquisitions had a positive impact of 1.0%. Foreign exchange increased sales by 0.1%.

  • The underlying trading operating profit (UTOP) margin was 16.9%, decreasing by 50 basis points. The trading operating profit (TOP) margin decreased by 200 basis points to 14.7%, mainly due to one-off items.

  • Underlying earnings per share increased by 8.1% in constant currency and increased by 7.3% on a reported basis to CHF 2.33. Earnings per share decreased by 9.5% to CHF 1.92 on a reported basis.

  • Free cash flow was CHF 1.5 billion, as working capital and capital expenditure increased temporarily in the context of supply chain constraints and high volume demand.

  • Continued portfolio management progress. In the second quarter, Nestlé Health Science agreed to acquire Puravida in Brazil and The Better Health Company in New Zealand.

  • Full-year 2022 outlook updated: we expect organic sales growth between 7% and 8%. The underlying trading operating profit margin is now expected around 17.0%. Underlying earnings per share in constant currency and capital efficiency are expected to increase.

Mark Schneider, Nestlé CEO, commented:"In the first half of the year, we delivered strong organic growth and a significant increase in underlying earnings per share. Our local teams implemented price increases in a responsible manner. Volume and product mix were resilient, based on our strong brands, differentiated offerings and leading market positions. We limited the impact of unprecedented inflationary pressures and supply chain constraints on our margin development through disciplined cost control and operational efficiencies. At the same time, investments behind capital expenditure, digitalization and sustainability increased significantly.

We are focused on creating shared value over both the short and long term. Growing food insecurity around the world and heightened climate concerns, following an increase in unusual weather patterns, underlines the importance of this strategic direction. Good for you and good for the planet are the two key strategic pillars that our company pursues in an unwavering manner, even in the face of significant short-term challenges."

Total Group

Zone North America

Zone Europe

Zone AOA

Zone Latin America

Zone Greater China

Nespresso

Nestlé Health Science

Other Businesses

Sales 6M-2022 (CHF m)

45 580

12 138

9 283

9 335

5 659

2 677

3 190

3 167

131

Sales 6M-2021 (CHF m)*

41 755

11 364

9 022

8 878

4 798

2 524

3 158

1 914

97

Real internal growth (RIG)**

1.7%

- 0.2%

2.1%

2.1%

4.2%

1.6%

- 1.6%

4.4%

31.1%

Pricing**

6.5%

9.8%

4.9%

6.1%

9.4%

0.7%

4.2%

2.2%

2.7%

Organic growth**

8.1%

9.6%

7.1%

8.2%

13.6%

2.3%

2.6%

6.6%

33.8%

Net M&A**

1.0%

- 7.1%

1.6%

- 0.1%

0.1%

0.0%

0.1%

57.2%

0.0%

Foreign exchange

0.1%

4.3%

- 5.7%

- 3.0%

4.3%

3.8%

- 1.7%

1.7%

0.3%

Reported sales growth

9.2%

6.8%

2.9%

5.2%

17.9%

6.0%

1.0%

65.5%

34.1%

6M-2022 Underlying TOP Margin

16.9%

18.8%

17.3%

23.5%

21.1%

15.0%

24.3%

13.7%

- 3.6%

6M-2021 Underlying TOP Margin*

17.4%

18.5%

18.7%

24.4%

21.0%

14.0%

26.0%

13.5%

7.6%

*2021 figures restated following the creation of Zone North America (NA) and Zone Greater China (GC) as of January 1, 2022. Zone AOA includes Middle East and North Africa (MENA) previously included in Zone EMENA
**RIG, pricing and organic growth figures exclude the Russia region, with a corresponding impact on the M&A and foreign exchange lines

Group sales

Organic growth was 8.1%. Pricing increased to 6.5% to reflect significant and unprecedented cost inflation. RIG was resilient at 1.7%, given the high base of comparison in 2021 and supply chain constraints.

Organic growth was 6.9% in developed markets, with strong pricing and positive RIG. Organic growth in emerging markets was 10.0%, with increased pricing and solid RIG.

By product category, Purina PetCare was the largest contributor to organic growth, with continued momentum for science-based and premium brands Purina Pro Plan, Purina ONE and Fancy Feast as well as veterinary products. Sales in coffee grew at a high single-digit rate, with broad-based growth across brands and geographies, supported by a strong recovery of out-of-home channels. Confectionery reported double-digit growth, reflecting particular strength for KitKat and seasonal products. Growth in Infant Nutrition reached a high single-digit rate, with a return to positive growth in China and improving market share trends. Water posted double-digit growth, led by premium brands and a further recovery of out-of-home channels. Nestlé Health Science recorded high single-digit growth, driven by Medical Nutrition and healthy-aging products. Dairy reported mid single-digit growth, with strong sales developments for coffee creamers and affordable nutrition offerings. Prepared dishes and cooking aids posted low single-digit growth, following a high base of comparison in 2021, with continued strong demand for Maggi. Sales in vegetarian and plant-based food continued to grow at a double-digit rate, led by Garden Gourmet.

By channel, organic growth in retail sales remained robust at 6.7%. Within retail, e-commerce sales grew by 8.3%, building on growth of 19.2% in the first half of 2021. Organic growth in out-of-home channels reached 29.6%, with sales exceeding 2019 levels.

Net acquisitions increased sales by 1.0%, largely related to the acquisitions of the core brands of The Bountiful Company as well as Orgain. The impact on sales from foreign exchange was positive at 0.1%. Total reported sales increased by 9.2% to CHF 45.6 billion.

Underlying Trading Operating Profit

Underlying trading operating profit increased by 6.0% to CHF 7.7 billion. The underlying trading operating profit margin decreased by 50 basis points to 16.9% in constant currency and on a reported basis, reflecting time delays between cost inflation and pricing actions.

Gross margin decreased by 280 basis points to 46.0%, following significant broad-based inflation for commodity, packaging, freight and energy costs. Pricing, growth leverage and efficiencies helped to significantly offset the impact of cost inflation.

Distribution costs as a percentage of sales decreased by 10 basis points, mainly as a result of the divestment of the Nestlé Waters North America brands.

Marketing and administration expenses as a percentage of sales decreased by 210 basis points, supported by sales growth leverage and disciplined cost control. Marketing spend decreased temporarily, following a lower level of promotion and marketing activities in the context of supply chain constraints.

Restructuring expenses and net other trading items were CHF 1.0 billion, reflecting higher impairments. As a result, trading operating profit decreased by 4.3% to CHF 6.7 billion, and the trading operating profit margin decreased by 200 basis points on a reported basis to 14.7%.

Net Financial Expenses and Income Tax

Net financial expenses increased by 4.5% to CHF 434 million, reflecting higher average net debt.

The Group reported tax rate increased by 680 basis points to 24.2% as a result of one-off items. The underlying tax rate increased by 70 basis points to 20.9%, mainly due to the geographic and business mix.

Net Profit and Earnings Per Share

Net profit decreased by 11.7% to CHF 5.2 billion. Net profit margin decreased by 270 basis points to 11.5% as a result of one-off items, including higher impairments and taxes. As a consequence, earnings per share decreased by 9.5% to CHF 1.92 on a reported basis.

Underlying earnings per share increased by 8.1% in constant currency and by 7.3% on a reported basis to CHF 2.33. The increase was mainly the result of strong organic growth. Nestlé's share buyback program contributed 1.7% to the underlying earnings per share increase, net of finance costs.

Cash Flow

Cash generated from operations decreased from CHF 5.8 billion to CHF 5.7 billion mainly due to an increase in working capital. The Group increased its inventory levels temporarily, due to significant supply chain constraints. Excluding the increase in working capital, cash generated from operations increased from CHF 7.9 billion to CHF 8.8 billion, driven by strong organic growth. Free cash flow decreased from CHF 2.8 billion to CHF 1.5 billion reflecting higher taxes and a temporary increase in capital expenditure to meet strong volume demand, particularly for Purina PetCare and coffee.

Share Buyback Program

In the first half, the Group repurchased CHF 6.9 billion of Nestlé shares as part of the three-year CHF 20 billion share buyback program, which began in January 2022.

Net Debt

Net debt increased to CHF 48.5 billion as at June 30, 2022, compared to CHF 32.9 billion at December 31, 2021. The increase largely reflected the dividend payment of CHF 7.6 billion and share buybacks of CHF 6.7 billion.

Portfolio Management

On April 1, 2022, Nestlé Health Science completed the acquisition of a majority stake in Orgain, a leader in plant-based nutrition. Orgain complements Nestlé Health Science's existing portfolio of nutrition products that support healthier lives. The deal is expected to be slightly accretive to Nestlé's organic growth, while slightly dilutive to the Group's underlying trading operating profit margin in 2022. The agreement includes the option for Nestlé Health Science to fully acquire Orgain in 2024.

On May 23, 2022, Nestlé Health Science agreed to acquire Puravida, a premium Brazilian nutrition and health lifestyle brand. The acquisition will enable Nestlé Health Science to expand its consumer health portfolio in Latin America.

On June 25, 2022, Nestlé Health Science agreed to acquire The Better Health Company. The acquisition includes the GO Healthy brand, New Zealand's leading supplement brand, and New Zealand Health Manufacturing, an Auckland-based manufacturing facility for vitamins, minerals and supplements. The acquisition will expand Nestlé Health Science's portfolio of vitamins, minerals and supplements in AOA.

Zone North America

  • 9.6% organic growth: - 0.2% RIG; 9.8% pricing.

  • The underlying trading operating profit margin increased by 30 basis points to 18.8% as a result of the Nestlé Waters North America brands divestment.

Sales 6M-2022

Sales 6M-2021

RIG

Pricing

Organic growth

UTOP 6M-2022

UTOP 6M-2021

Margin 6M-2022

Margin 6M-2021

Zone North America

CHF 12.1 bn

CHF 11.4 bn

- 0.2%

9.8%

9.6%

CHF 2.3 bn

CHF 2.1 bn

18.8%

18.5%

Organic growth was 9.6%, with increased pricing of 9.8%. RIG was - 0.2%, following a high base of comparison in 2021 and supply chain constraints. Net divestitures reduced sales by 7.1%, mainly due to the divestment of the Nestlé Waters North America brands. Foreign exchange had a positive impact of 4.3%. Reported sales in Zone North America increased by 6.8% to CHF 12.1 billion.

Organic growth in Zone North America was close to a double-digit rate, led by increased pricing, strong momentum in e-commerce and a further recovery of out-of-home channels. The Zone saw continued broad-based market share gains, particularly in pet food, coffee and creamers as well as premium water.

By product category, Purina PetCare was the largest growth contributor with strong momentum across channels and brands. Purina Pro Plan, including veterinary products, Fancy Feast and Purina ONE all posted strong double-digit growth, helped by continued innovation such as Purina ONE Microbiome Balance. Sales in Nestlé Professional and Starbucks out-of-home products grew at a strong double-digit rate. The beverages category, including Starbucks at-home products, Coffee mate and Nescafé, saw mid single-digit growth, following a high base of comparison in 2021. Sales in premium water grew at a double-digit rate, with strong momentum for S.Pellegrino, Perrier and Essentia. Infant formula recorded strong growth, following supply shortages in the market. Nestlé helped address the needs of parents and caregivers by importing essential infant formula products to the United States. Baby food also posted strong growth, fueled by new launches for Gerber in healthy snacking and high demand for organic plant-based offerings. Frozen food reported low single-digit growth, impacted by a high base of comparison in 2021 for frozen meals. DiGiorno and Hot Pockets saw solid demand, and growth in Stouffer's turned positive in the second quarter. Ready-to-drink Nesquik in the U.S. and confectionery in Canada saw double-digit growth, supported by new product launches.

The Zone's underlying trading operating profit margin increased by 30 basis points. Excluding the impact of the Nestlé Waters North America brands divestment, the Zone's margin development was negative as pricing did not fully offset significant cost inflation.

Zone Europe

Sales 6M-2022

Sales 6M-2021

RIG

Pricing

Organic growth

UTOP 6M-2022

UTOP 6M-2021

Margin 6M-2022

Margin 6M-2021

Zone Europe*

CHF 9.3 bn

CHF 9.0 bn

2.1%

4.9%

7.1%

CHF 1.6 bn

CHF 1.7 bn

17.3%

18.7%

*RIG, pricing and organic growth figures exclude the Russia region, with a corresponding impact on the M&A and foreign exchange lines

Organic growth was 7.1%. Pricing reached 4.9%. RIG remained solid at 2.1%, despite a high base of comparison in 2021 and supply chain constraints. Foreign exchange negatively impacted sales by 5.7%. Reported sales in Zone Europe increased by 2.9% to CHF 9.3 billion.

Zone Europe reported high single-digit organic growth, reflecting increased pricing, a further recovery of out-of-home channels and innovation. The Zone continued to see market share gains, particularly in pet food, coffee and Infant Nutrition.

By product category, the key growth driver was Purina PetCare, fueled by premium brands Gourmet, Purina ONE and Purina Pro Plan, including veterinary products. Growth was broad-based across channels, particularly in e-commerce and pet specialty stores. Gourmet Revelations, the recently launched super-premium cat food, saw strong demand. Sales in Nestlé Professional grew at a double-digit rate, led by beverages. Water posted double-digit growth, driven by S.Pellegrino, Perrier and Acqua Panna. Sales in Infant Nutrition grew at a double-digit rate, based on strong momentum for human milk oligosaccharides (HMOs) products. Confectionery reported mid single-digit growth, with strong demand for KitKat across most geographies and Baci in Italy. Coffee posted low single-digit growth, led by Nescafé soluble coffee. Starbucks by Nespresso and other Nespresso-compatible capsules saw further market share gains in the retail segment. Culinary reported a sales decrease, impacted by negative growth in pizza and noodles. Garden Gourmet plant-based products continued to see strong momentum, reflecting new product launches.

The Zone's underlying trading operating profit margin decreased by 140 basis points. Significant cost inflation more than offset pricing, growth leverage and disciplined cost control.

Zone Asia, Oceania and Africa (AOA)

Sales 6M-2022

Sales 6M-2021

RIG

Pricing

Organic growth

UTOP 6M-2022

UTOP 6M-2021

Margin 6M-2022

Margin 6M-2021

Zone AOA

CHF 9.3 bn

CHF 8.9 bn

2.1%

6.1%

8.2%

CHF 2.2 bn

CHF 2.2 bn

23.5%

24.4%

Organic growth reached 8.2%, with RIG of 2.1%. Pricing increased to 6.1%, with broad-based contributions from all geographies and categories. Foreign exchange reduced sales by 3.0%. Reported sales in Zone AOA increased by 5.2% to CHF 9.3 billion.

Organic growth in Zone AOA accelerated to a high single-digit rate, driven by increased pricing, a further recovery of out-of-home channels and strong supply chain execution. The Zone saw market share gains across categories, particularly in culinary, portioned and ready-to-drink coffee as well as dairy.

South-East Asia posted mid single-digit growth, with positive contributions from most geographies, led by Malaysia. Nescafé, particularly ready-to-drink offerings, as well as Maggi and KitKat saw strong demand. South Asia recorded broad-based double-digit growth, due to distribution expansion and increased brand equity, particularly for Maggi, KitKat and Nescafé. Growth in Middle East and Africa was close to a double-digit rate, based on strong momentum for affordable offerings in Central and West Africa. Japan reported mid single-digit growth, based on solid demand for coffee and Purina PetCare. Sales in South Korea grew at a double-digit rate, driven by Starbucks products. Oceania reported high single-digit growth, fueled by new product launches, including KitKat Dark Tablet and the relaunch of Nescafé coffee mixes.

By product category, culinary was the largest growth contributor, led by Maggi. Coffee posted high single-digit growth, with continued strong demand for Nescafé and Starbucks products. Sales in Nestlé Professional grew at a double-digit rate. Infant Nutrition reported mid single-digit growth, with a broad-based recovery in the second quarter. Sales in cocoa and malt beverages as well as confectionery saw double-digit growth, based on strong demand for Milo and KitKat. Purina PetCare recorded high single-digit growth, with continued momentum for Purina ONE, Purina Pro Plan and Felix.

The Zone's underlying trading operating profit margin decreased by 90 basis points. Significant cost inflation more than offset pricing, growth leverage and disciplined cost control.

Zone Latin America

Sales 6M-2022

Sales 6M-2021

RIG

Pricing

Organic growth

UTOP 6M-2022

UTOP 6M-2021

Margin 6M-2022

Margin 6M-2021

Zone Latin America

CHF 5.7 bn

CHF 4.8 bn

4.2%

9.4%

13.6%

CHF 1.2 bn

CHF 1.0 bn

21.1%

21.0%

Organic growth was 13.6%, with increased pricing of 9.4%. RIG remained strong at 4.2%, following high single-digit growth in 2021. Foreign exchange had a positive impact of 4.3%. Reported sales in Zone Latin America increased by 17.9% to CHF 5.7 billion.

Zone Latin America maintained double-digit organic growth, with broad-based contributions across geographies and categories. Growth was supported by increased pricing, a further recovery of out-of-home channels and sustained momentum for retail sales. The Zone saw market share gains in Infant Nutrition, pet food and coffee creamers.

Sales in Brazil grew at a double-digit rate, with strong momentum for confectionery, cocoa and malt beverages as well as Infant Nutrition. Mexico reported high single-digit growth, with strong sales developments for Purina PetCare, Nescafé and Carnation. Sales in Chile grew at a double-digit rate, led by confectionery, Purina PetCare and coffee. Colombia and the Plata Region also saw strong growth, supported by volumes.

By product category, confectionery was the largest growth contributor, reflecting strong demand for KitKat and key local brands, particularly Garoto in Brazil. Sales in Purina PetCare grew at a double-digit rate, fueled by Dog Chow, Cat Chow and Purina Pro Plan. Distribution of Purina ONE continued to expand across the Zone. Coffee reported broad-based double-digit growth, supported by Nescafé soluble coffee, Nescafé Dolce Gusto and the further roll-out of Starbucks products. Sales in Nestlé Professional grew at a strong double-digit rate, with particular strength for beverages. Infant Nutrition saw high single-digit growth, based on solid momentum for Nido and NAN. Dairy posted mid single-digit growth, led by fortified milks and dairy culinary solutions.

The Zone's underlying trading operating profit margin increased by 10 basis points. Pricing, growth leverage and disciplined cost control more than offset cost inflation.

Zone Greater China

Sales 6M-2022

Sales 6M-2021

RIG

Pricing

Organic growth

UTOP 6M-2022

UTOP 6M-2021

Margin 6M-2022

Margin 6M-2021

Zone Greater China

CHF 2.7 bn

CHF 2.5 bn

1.6%

0.7%

2.3%

CHF 0.4 bn

CHF 0.4 bn

15.0%

14.0%

Organic growth was 2.3%, with RIG of 1.6%. Pricing reached 0.7%, turning positive in the second quarter. Foreign exchange had a positive impact of 3.8%. Reported sales in Zone Greater China increased by 6.0% to CHF 2.7 billion.

Zone Greater China reported low single-digit organic growth, impacted by COVID-19-related movement restrictions. Growth was supported by robust demand in e-commerce channels and continued innovation.

By product category, coffee posted mid single-digit growth. Starbucks products and Nescafé soluble coffee saw continued momentum. Culinary reported mid single-digit growth, helped by increased distribution and new product launches. Confectionery recorded mid single-digit growth, led by strong sales development for Shark wafer chocolate and solid demand for Hsu Fu Chi. Purina PetCare posted high single-digit growth, with particular strength for Mon Petit, Fancy Feast and recently launched DentaLife. Growth in Infant Nutrition turned positive, with improving market share trends. The business saw a strong recovery in the second quarter, particularly for NAN and illuma. Nestlé Professional reported a sales decrease, reflecting restrictions on out-of-home channels.

The Zone's underlying trading operating profit margin increased by 100 basis points. Favorable mix and disciplined cost control more than offset cost inflation.

Nespresso

Sales 6M-2022

Sales 6M-2021

RIG

Pricing

Organic growth

UTOP 6M-2022

UTOP 6M-2021

Margin 6M-2022

Margin 6M-2021

Nespresso*

CHF 3.2 bn

CHF 3.2 bn

- 1.6%

4.2%

2.6%

CHF 0.8 bn

CHF 0.8 bn

24.3%

26.0%

*RIG, pricing and organic growth figures exclude the Russia region, with a corresponding impact on the M&A and foreign exchange lines

Organic growth was 2.6%, with increased pricing of 4.2%. RIG was - 1.6% following strong double-digit growth in 2021 during the pandemic. Foreign exchange negatively impacted sales by 1.7%. Reported sales in Nespresso increased by 1.0% to CHF 3.2 billion.

Nespresso reported low single-digit organic growth, following strong double-digit growth in 2021. Out-of-home channels saw further recovery, with strong demand for the Momento system. The Vertuo system saw sustained momentum and is now sold in 44 countries. Innovation continued to resonate with consumers with new product launches, including the summer collection of Barista Creations Liminha over Ice and Exotic Liminha over Ice.

By geography, North America posted double-digit growth with continued market share gains. Europe reported a sales decrease, following a high base of comparison in 2021. Other regions combined recorded high single-digit growth.

In the second quarter, Nespresso obtained global certification as a B Corp, reflecting the business's ongoing commitment to sustainability and transparency.

The underlying trading operating profit margin of Nespresso decreased by 170 basis points, impacted by investments in the roll-out of the Vertuo system and cost inflation.

Nestlé Health Science

Sales 6M-2022

Sales 6M-2021

RIG

Pricing

Organic growth

UTOP 6M-2022

UTOP 6M-2021

Margin 6M-2022

Margin 6M-2021

Nestlé Health Science*

CHF 3.2 bn

CHF 1.9 bn

4.4%

2.2%

6.6%

CHF 0.4 bn

CHF 0.3 bn

13.7%

13.5%

*RIG, pricing and organic growth figures exclude the Russia region, with a corresponding impact on the M&A and foreign exchange lines

Organic growth was 6.6%, with robust RIG of 4.4% and increased pricing of 2.2%. Net acquisitions increased sales by 57.2%, largely related to the acquisition of the core brands of The Bountiful Company as well as Orgain. Foreign exchange positively impacted sales by 1.7%. Reported sales in Nestlé Health Science increased by 65.5% to CHF 3.2 billion.

Nestlé Health Science posted high single-digit organic growth, building on strong sales developments in 2020 and 2021. Growth was supported by innovation, geographic expansion and market share gains.

Consumer Care posted mid single-digit growth. Healthy-aging products grew at a double-digit rate, supported by Boost and Nutren. Vitamins, minerals and supplements reported low single-digit growth, following a high base of comparison and supply chain constraints. Sales of Pure Encapsulations, a super-premium offering recommended by healthcare professionals, grew at a double-digit rate. Vital Proteins saw robust demand, helped by geographic expansion. Orgain, the newly acquired plant-based nutrition business, posted strong double-digit growth, based on innovation and increased distribution.

Medical Nutrition reported double-digit growth, with strong sales developments for pediatric products, Althéra, Alfaré and Alfamino. Zenpep posted strong growth with market share gains. Palforzia, the peanut allergy treatment, saw further patient adoption.

By geography, sales in North America grew at a high single-digit rate. Europe saw positive growth. Other regions combined posted double-digit growth.

The underlying trading operating profit margin of Nestlé Health Science increased by 20 basis points. Growth leverage and acquisition synergies more than offset cost inflation and growth investments.

Business as a force for good: Improving the lives of lower-income consumers through affordable nutrition

Supply chain disruptions and inflationary pressures have been exacerbated by the war in Ukraine and extreme weather events related to climate change. People's purchasing power has been reduced. In this context, offering affordable, nutritious food to lower-income consumers is more important than ever.

Working to make nutritious food products affordable and accessible is part of Nestlé's mission. The company focuses on four areas:

  • Micronutrient deficiencies are widespread globally. Nestlé helps tackle the issue through micronutrient fortification based on local needs. In Pakistan, for example, one out of two children are deficient in iron. The company recently launched BUNYAD IRON+, an affordable dairy-based drink fortified with a new source of iron that is more easily absorbed in the body. In the Central and West Africa Region (CWAR), where iron deficiency is also widespread, Nestlé fortifies Maggi bouillon with iron and iodine. These products are used widely and regularly in the region to add flavor to home-cooked meals. Last year, Nestlé sold 82 billion fortified servings of affordable Maggi bouillon in CWAR alone. Nestlé also addresses inadequacies in macronutrients, like fiber, healthy fats and protein, through its products.

  • To increase the availability and accessibility of affordable nutrition products, Nestlé aims to offer them at a price people can afford on their daily wages. It's also about making products available wherever consumers shop. In remote areas around the world, Nestlé leverages different channels specific to local markets to distribute its affordable nutrition products. The traditional open markets in CWAR, where Maggi bouillon is sold, is just one example.

  • Nestlé works on value chain optimization to keep costs low and secure supply. It sources ingredients from local producers and strives to minimize food waste. Nestlé Cerevita Instant Sour Porridge, for instance, is an affordable nutritious solution for consumers in southern Africa. It uses high-quality ingredients that are locally and sustainably sourced. Production of the product leverages existing roller drying and dry-mixing technologies. In this way, Nestlé minimizes production costs and provides a porridge that is adapted to local consumer taste preferences and nutritional requirements.

  • Nestlé is expanding its nutrition education programs and partnerships to help consumers. For example, its 'Live Strong with Iron' campaign in CWAR promotes the awareness and consumption of iron-rich foods. In Australia, Nestlé developed and produced the first custom-made product for Foodbank, a food relief organization. The Maggi Hearty One Pot Recipe Mix is used in combination with the fresh ingredients Foodbank provides and has added flavor to one million meals so far. The product is helping fight food insecurity and minimizing food waste at the same time.

Outlook

Full-year 2022 outlook updated: we expect organic sales growth between 7% and 8%. The underlying trading operating profit margin is now expected around 17.0%. Underlying earnings per share in constant currency and capital efficiency are expected to increase.

Annex

Half-year sales and underlying trading operating profit (UTOP) overview by operating segment

Total Group

Zone North America

Zone Europe

Zone AOA

Zone Latin America

Zone Greater China

Nespresso

Nestlé Health Science

Other Businesses

Sales 6M-2022 (CHF m)

45 580

12 138

9 283

9 335

5 659

2 677

3 190

3 167

131

Sales 6M-2021 (CHF m)*

41 755

11 364

9 022

8 878

4 798

2 524

3 158

1 914

97

Real internal growth (RIG)**

1.7%

- 0.2%

2.1%

2.1%

4.2%

1.6%

- 1.6%

4.4%

31.1%

Pricing**

6.5%

9.8%

4.9%

6.1%

9.4%

0.7%

4.2%

2.2%

2.7%

Organic growth**

8.1%

9.6%

7.1%

8.2%

13.6%

2.3%

2.6%

6.6%

33.8%

Net M&A**

1.0%

- 7.1%

1.6%

- 0.1%

0.1%

0.0%

0.1%

57.2%

0.0%

Foreign exchange

0.1%

4.3%

- 5.7%

- 3.0%

4.3%

3.8%

- 1.7%

1.7%

0.3%

Reported sales growth

9.2%

6.8%

2.9%

5.2%

17.9%

6.0%

1.0%

65.5%

34.1%

6M-2022 Underlying TOP (CHF m)

7 683

2 284

1 606

2 198

1 196

400

777

435

- 5

6M-2021 Underlying TOP (CHF m)*

7 251

2 104

1 686

2 162

1 008

352

822

258

7

6M-2022 Underlying TOP Margin

16.9%

18.8%

17.3%

23.5%

21.1%

15.0%

24.3%

13.7%

- 3.6%

6M-2021 Underlying TOP Margin*

17.4%

18.5%

18.7%

24.4%

21.0%

14.0%

26.0%

13.5%

7.6%

*2021 figures restated following the creation of Zone North America (NA) and Zone Greater China (GC) as of January 1, 2022. Zone AOA includes Middle East and North Africa (MENA) previously included in Zone EMENA
**RIG, pricing and organic growth figures exclude the Russia region, with a corresponding impact on the M&A and foreign exchange lines

Half-year sales and underlying trading operating profit (UTOP) overview by product

Total Group

Powdered & liquid beverages

Water

Milk products & ice cream

Nutrition & Health Science

Prepared dishes & cooking aids

Confec-tionery

PetCare

Sales 6M-2022 (CHF m)

45 580

12 335

1 792

5 443

7 689

6 137

3 595

8 589

Sales 6M-2021 (CHF m)

41 755

11 648

2 291

5 205

6 060

5 919

3 229

7 403

Real internal growth (RIG)**

1.7%

1.3%

8.8%

- 3.3%

4.2%

- 5.0%

6.8%

5.1%

Pricing**

6.5%

6.2%

8.4%

6.8%

3.6%

7.9%

4.0%

8.8%

Organic growth**

8.1%

7.6%

17.2%

3.5%

7.8%

2.9%

10.8%

13.9%

6M-2022 Underlying TOP (CHF m)

7 683

2 915

175

1 192

1 502

974

498

1 635

6M-2021 Underlying TOP (CHF m)

7 251

2 905

204

1 309

1 079

962

372

1 568

6M-2022 Underlying TOP Margin

16.9%

23.6%

9.7%

21.9%

19.5%

15.9%

13.8%

19.0%

6M-2021 Underlying TOP Margin

17.4%

24.9%

8.9%

25.2%

17.8%

16.3%

11.5%

21.2%

**RIG, pricing and organic growth figures exclude the Russia region, with a corresponding impact on the M&A and foreign exchange lines

Contacts:

Media:
Christoph Meier  Tel.: +41 21 924 2200
mediarelations@nestle.com

Investors:
Luca Borlini  Tel.: +41 21 924 3509
ir@nestle.com

Wed, 27 Jul 2022 17:18:00 -0500 en-CA text/html https://ca.sports.yahoo.com/news/nestl-reports-half-results-2022-051500925.html
Killexams : U.S. considers crackdown on memory chip makers in China

By Alexandra Alper and Karen Freifeld

WASHINGTON (Reuters) - The United States is considering limiting shipments of American chipmaking equipment to memory chip makers in China including Yangtze Memory Technologies Co Ltd (YMTC), according to four people familiar with the matter, part of a bid to halt China's semiconductor sector advances and protect U.S. companies.

If President Joe Biden's administration proceeds with the move, it could also hurt South Korean memory chip juggernauts Samsung Electronics Co Ltd and SK Hynix Inc, the sources said, speaking on condition of anonymity. Samsung has two big factories in China while SK Hynix Inc is buying Intel Corp's NAND flash memory chips manufacturing business in China.

The crackdown, if approved, would involve barring the shipment of U.S. chipmaking equipment to factories in China that manufacture advanced NAND chips.

It would mark the first U.S. bid through export controls to target Chinese production of memory chips without specialized military applications, representing a more expansive view of American national security, according to export control experts.

The move also would seek to protect the only U.S. memory chip producers, Western Digital Corp and Micron Technology Inc, which together represent about a quarter of the NAND chips market.

NAND chips store data in devices such as smartphones and personal computers and at data centers for the likes of Amazon, Facebook and Google. How many gigabytes of data a phone or laptop can hold is determined by how many NAND chips it includes and how advanced they are.

Under the action being considered, U.S. officials would ban the export of tools to China used to make NAND chips with more than 128 layers, according to two of the sources. LAM Research Corp and Applied Materials, both based in Silicon Valley, are the primary suppliers of such tools.

All the sources described the administration's consideration of the matter as in the early stages, with no proposed regulations yet drafted.

Asked to comment on the possible move, a spokesperson for the Commerce Department, which oversees export controls, did not discuss potential restrictions but noted that "the Biden administration is focused on impairing (China's) efforts to manufacture advanced semiconductors to address significant national security risks to the United States."

FAST-GROWING COMPANY

YMTC, founded in 2016, is a rising power in manufacturing NAND chips. Micron and Western Digital are under pressure from YMTC's low prices, as the White House wrote in a June 2021 report https://www.whitehouse.gov/wp-content/uploads/2021/06/100-day-supply-chain-review-report.pdf. YMTC's expansion and low-price offerings present "a direct threat" to Micron and Western Digital, that report said. The report described YMTC as China's "national champion" and the recipient of some $24 billion in Chinese subsidies.

YMTC, already under investigation by the Commerce Department over whether it violated U.S. export controls by selling chips to Chinese telecoms company Huawei, is in talks with Apple Inc to supply the top U.S. smartphone maker with flash memory chips, according to a Bloomberg report.

LAM Research Corp, SK Hynix and Micron declined comment on the U.S. policy. Samsung, Applied Materials Inc, YMTC and Western Digital Corp did not immediately respond to requests for comment.

CONGRESS ACTS

Tensions between China and the United States over the tech sector deepened under Biden's predecessor Donald Trump and have continued since. Reuters reported on July 8 that Biden's administration is also considering restrictions on shipments to China of tools to make advanced logic chips, seeking to hamstring China's largest chipmaker, SMIC.

The U.S. Congress last week approved legislation aimed at helping the United States compete with China by investing billions of dollars in domestic chip production.

Chipmakers that take money under the measure would be prohibited from building or expanding manufacturing for certain advanced chips, including advanced memory chips at a level to be determined by the administration, in countries including China.

According to Walt Coon of the consulting firm Yole Intelligence, YMTC accounts for about 5% of worldwide NAND flash memory chip production, almost double from a year ago. Western Digital stands at about 13% and Micron 11%. Coon said YMTC would be greatly hurt by restrictions like those that Biden's administration is contemplating.

"If they were stuck at 128, I don't know how they would really have a path forward," Coon said.

Production of NAND chips in China has grown to more than 23% of the worldwide total this year from under 14% in 2019, while production in the United States has decreased from 2.3% to 1.6% over the same period, Yole data showed. For the American companies, nearly all of their chip production is done overseas.

It was unclear what impact the potential restrictions might have on other players in China. Intel, which retains a contract to manage operations in the factory it is selling to SK Hynix in China, is already producing memory chips with 144 layers at the Chinese site, according to an Intel press release.

(Reporting by Alexandra Alper and Karen Freifeld; Additional reporting by Stephen Nellis; Editing by Chris Sanders and Will Dunham)

Sun, 31 Jul 2022 22:07:00 -0500 en-CA text/html https://ca.finance.yahoo.com/news/u-considers-crackdown-memory-chip-100425708.html
Killexams : Video Conferencing Market worth $22.5 billion by 2026 - Report by MarketsandMarkets™

MarketsandMarkets Research Pvt. Ltd.

Chicago, Aug. 05, 2022 (GLOBE NEWSWIRE) -- Video Conferencing Market size is expected to grow from USD 9.2 billion in 2021 to USD 22.5 billion by 2026, at a Compound Annual Growth Rate (CAGR) of 19.7% during the forecast period, according to a new report by MarketsandMarkets™. With COVID-19, the entire workforce has experienced a transition toward remote working, paving a way for video conferencing solution and hardware products. The reduced travel time and cost, the importance of involving employees in determining strategic goals, and the rising need for virtual meeting rooms have overall increased the spending of companies on video conferencing solutions.

Download PDF Brochure: https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=99384414

Browse in-depth TOC on "Video Conferencing Market
204 - Tables
41 - Figures
237 - Pages

Scope of the Report

Report Metrics

Details

Market size available for years

2020-2026

Base year considered

2020

Forecast period

2022-2026

Forecast units

Value (USD Million)

Estimated Year Market Size

USD 9.2 billion in 2021

Forecast Year Market Size

USD 22.5 billion by 2026

Segments covered

Component, vertical, deployment mode, application, and region.

Regions covered

North America, Europe, APAC, Middle East and Latin America

Companies covered

Microsoft (US), Zoom (US), Cisco (US), Adobe (US), Huawei (China), Google(US), Avaya (US), AWS (US), Poly (US), LogMeIn (US), Enghouse Systems (Canada), Pexip (Norway), Qumu (US), Sonic Foundry (US), Lifesize (US), Kaltura (US), BlueJeans Network (US), Kollective Technology (US), StarLeaf(UK), HighFive (US), Logitech (Switzerland), Barco (Belgium), Fuze (US), Haivision (Canada) and Premium Global Services (US).

Cloud mode of deployment segment is expected to grow at the highest CAGR during the forecast period


The cloud deployment model includes providers, such as the Infrastructure as a Service (IaaS) and the Software as a Service (SaaS), with the majority of end users as enterprises, government agencies, and healthcare organizations. SaaS-based video Solution are deployed leveraging their simplicity and ease of deployment. Enterprises are considering privacy policy and the data security model of cloud service, and the SLAs of the provider before subscribing to the SaaS model of cloud deployment. IaaS provides an organization with control over its data privacy and scalability management, hosting its on-premises data to the cloud. Video conferencing applications that are designed for self-hosting on IaaS platforms are referred self-hosting. IaaS providers, such as Microsoft, Google, Oracle, and Amazon, provide the enterprises with their data center available in most major metro areas. They offer with a global resilient network with large numbers of Points of Presence (PoP) near offices. IaaS is leveraged for both virtual private cloud and complete private cloud environments.

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Healthcare segment to grow at the highest CAGR during the forecast period

The healthcare and life sciences vertical deals with diverse clinical, administrative, and financial content on a daily basis. This results in the requirement for channelized content insights and accurate clinical information that can be consolidated through video conferencing Solution. The collaborations enable healthcare providers in telemedicine and patient care, medical education, and healthcare administration applications to offer enhanced patient care by providing them with improved communication options. The solution enables face-to-face interactions between patients, healthcare teams, and family members to discuss various treatment options, located anywhere in the world. Video conferencing technology also helps with patient monitoring, consulting, and counselling.

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Asia Pacific (APAC) region to record the highest growing region in the Video Conferencing Market

APAC has several growing economies, such as China, Australia and Japan, which are expected to register high growth in the Video Conferencing Market. These countries have always supported and promoted industrial and technological growth. In addition, they possess a developed technological infrastructure, which is promoting the adoption of video conferencing solutions across all industry verticals. The network market in APAC is driven by the growing acceptance of cloud-based solutions, emerging technologies such as the IoT, and big data analytics and mobility.

Key and innovative vendors in Video Conferencing Market are Microsoft (US), Zoom (US), Cisco (US), Adobe (US), Huawei (China), Google (US), Avaya (US), AWS (US), Poly (US), LogMeIn (US), Enghouse Systems (Canada), Pexip (Norway), Qumu (US), Sonic Foundry (US), Lifesize (US), Kaltura (US), BlueJeans Network (US), Kollective Technology (US), StarLeaf (UK), HighFive (US), Logitech (Switzerland), Barco (Belgium), Fuze (US), Haivision (Canada) and Premium Global Services (US).

Browse Adjacent Markets: Software & Services Research Reports & Consulting

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Video Analytics Market by Component, Application (Intrusion Management, Incident Detection, People/Crowd Counting, Traffic Monitoring), Deployment Model (On-premises and Cloud), Type, Vertical, and Region - Global Forecast to 2026

CONTACT: About MarketsandMarkets™ MarketsandMarkets™ provides quantified B2B research on 30,000 high growth niche opportunities/threats which will impact 70% to 80% of worldwide companies’ revenues. Currently servicing 7500 customers worldwide including 80% of global Fortune 1000 companies as clients. Almost 75,000 top officers across eight industries worldwide approach MarketsandMarkets™ for their painpoints around revenues decisions. Our 850 fulltime analyst and SMEs at MarketsandMarkets™ are tracking global high growth markets following the "Growth Engagement Model – GEM". The GEM aims at proactive collaboration with the clients to identify new opportunities, identify most important customers, write "Attack, avoid and defend" strategies, identify sources of incremental revenues for both the company and its competitors. MarketsandMarkets™ now coming up with 1,500 MicroQuadrants (Positioning top players across leaders, emerging companies, innovators, strategic players) annually in high growth emerging segments. MarketsandMarkets™ is determined to benefit more than 10,000 companies this year for their revenue planning and help them take their innovations/disruptions early to the market by providing them research ahead of the curve. MarketsandMarkets’s flagship competitive intelligence and market research platform, "Knowledge Store" connects over 200,000 markets and entire value chains for deeper understanding of the unmet insights along with market sizing and forecasts of niche markets. Contact: Mr. Aashish Mehra MarketsandMarkets™ INC. 630 Dundee Road Suite 430 Northbrook, IL 60062 USA: +1-888-600-6441 Email: sales@marketsandmarkets.com
Fri, 05 Aug 2022 02:30:00 -0500 en-CA text/html https://ca.news.yahoo.com/video-conferencing-market-worth-22-143000618.html Killexams : Lake Resources shares hit by short seller's lithium tech allegations

(Reuters) - Short seller J Capital Research on Monday alleged that Lake Resources NL's plan to produce lithium in Argentina is based on a process from Lilac Solutions Inc that likely does not work, the latest attack against a wave of new technologies aiming to produce the electric vehicle battery metal.

Shares of Lake, which are traded in Australia, fell 6.3% on Monday after J Capital's report https://www.jcapitalresearch.com/uploads/2/0/0/3/20032477/2022_07_11_lke.pdf outlined several alleged missteps by Lake's management and claimed that technology developed by Lilac is too costly to run and uses too much freshwater.

Privately-held Lilac is among the most-prominent developers of so-called direct lithium extraction (DLE) technologies aiming to extract the battery metal from brine using a range of equipment, though none have worked at commercial scale. (Full story) https://www.reuters.com/business/sustainable-business/new-lithium-technology-can-help-world-go-green-if-it-works-2022-04-07 (Full story) https://www.reuters.com/article/mining-lithium-technology-idCNL1N2UK302

"Lake has hitched its cart to Lilac's yet-to-be-proven technology," J Capital Research said in the 17-page report. "Investors still have no evidence that the Lilac DLE technology works at scale, and if so, at what cost."

Lilac signed a deal with Lake last September to develop the Kachi lithium project in Argentina, part of a plan to evolve from a technology company to a lithium producer. https://www.reuters.com/business/sustainable-business/australias-lake-resources-teams-up-with-clean-tech-firm-lilac-develop-argentina-2021-09-21/#:~:text=MELBOURNE%2C%20Sept%2022%20(Reuters),rocketing%20more%20than%2020%25%20higher

In April, Ford Motor Co signed a preliminary lithium supply deal with Lake. (Full story) https://www.reuters.com/article/ford-motor-lithium-lake-resources-idCAKCN2M31K1

Representatives for Lake could not immediately be reached for comment. J Capital declined to disclose the size of its short position.

Lilac's technology uses ceramic beads to attract lithium in batch cycles, akin to a laundry machine, after which a water-and-acid mixture is used to wash off the metal.

J Capital alleges in the report that the beads only work for 150 cycles, making Lake's project uneconomical.

Lilac Chief Executive Dave Snydacker said that figure is "factually inaccurate" and that his company has tested the beads at more than 1,000 cycles.

"I don't know where they got that number from. Maybe they're guessing," Snydacker told Reuters, adding his company expects to deliver a pilot plant to Lake's Kachi site by the end of the month.

"We have a high degree of confidence that our plant will be successful because we've supported the design with so much test work."

(Reporting by Ernest Scheyder; Editing by Marguerita Choy)

Mon, 11 Jul 2022 00:52:00 -0500 en-CA text/html https://ca.finance.yahoo.com/news/lake-resources-shares-hit-short-195220109.html
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